In this talk at the Longevity Med Summit, I will delve into the remarkable potential of molecular hydrogen, an often underrated molecule, to influence longevity and mitochondrial health. The discussion will encompass various facets, including: 1. Introduction to Molecular Hydrogen Effects: Understanding the profound impact of molecular hydrogen on cellular processes and overall health. 2. Research Insights: An overview of recent research findings and studies that have explored the effects of molecular hydrogen on longevity, mitochondrial function, and cellular dynamics. 3. Mitochondrial Function Enhancement: How molecular hydrogen plays a pivotal role in mitigating mitochondrial dysfunction, promoting mitochondrial biogenesis, and regulating mitochondrial dynamics. 4. Cellular Energy Boost: Discussing how molecular hydrogen activates mitochondrial unfolded protein response (mtUPR) and mitochondrial ATP-sensitive potassium channels (MitoKATPs), contributing to increased ATP production and improved cellular energy. 5. Redox Pathway Modulation: Insights into how molecular hydrogen can modulate essential cellular redox pathways, including NADP/NADPH, to maintain cellular balance. 6. Synergy with Other Therapies: Exploring the synergies between molecular hydrogen and other longevity-enhancing therapies, such as IHHT, supplements, and nutrition. 7. Practical Integration in Clinical and Ambulant Settings: Demonstrating how molecular hydrogen can be practically integrated into clinical and ambulant settings, offering accessible and effective solutions for improving longevity and mitochondrial health. By the end of this talk, attendees will gain a comprehensive understanding of how molecular hydrogen, often overlooked, can be a game-changer in the pursuit of longevity and improved mitochondrial health, both as a standalone therapy and in conjunction with other interventions, with practical applications in clinical and ambulant contexts.